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Alto Neuroscience (ANRO) Reports FY25 Loss of $2.19/Share

Alto Neuroscience reports Q4 loss of $2.19/share, 434% wider than the $0.41 estimate, with zero revenue as clinical-stage biotech continues development.

March 16, 2026 2 min read
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Alto Neuroscience reports Q4 loss of $2.19/share, 434% wider than the $0.41 estimate, with zero revenue as clinical-stage biotech continues development.

Earnings Per Share (GAAP)
$-2.19
vs $-0.41 est.
Revenue
$0
vs $0 est.

Loss Narrows. Alto Neuroscience, Inc. (NYSE: ANRO) reported a loss of $2.19 per share for fiscal 2025, narrower than $2.50 per share last year. The biotechnology company’s operating loss totaled $66.4 million for the year. The company reported no revenue.

Pre-revenue biotech trajectory. Alto Neuroscience remains in the clinical development stage with no commercial products generating sales. Revenue has held at zero across the trailing four quarters. The $691.5 million market capitalization reflects investor expectations for the company’s neuroscience pipeline rather than current commercial operations.

Analyst sentiment remains constructive. Despite the loss, the analyst community maintains a bullish stance with 9 Buy ratings and 1 Hold rating among the 10 analysts covering the stock. Shares closed at $22.23, near the 52-week high of $23.56 and well above the 52-week low of $1.60. Trading volume reached 250,901 shares.

What to Watch: Monitor the company’s next clinical trial readout and cash runway disclosure in the 10-K filing. With operating losses exceeding $66 million, the burn rate and financing strategy will determine how long Alto can fund its neuroscience programs before needing additional capital.

This article was generated using AlphaStreet’s proprietary financial analysis technology and reviewed by our editorial team.

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Tags: #ANRO