BioLife Solutions Inc. (NASDAQ: BLFS) Q1 2022 earnings call dated May. 09, 2022
Corporate Participants:
Troy Wichterman — Chief Financial Officer
Michael Rice — Chairman & Chief Executive Officer
Rod de Greef — Chief Operating Officer
Analysts:
Max Masucci — Cowen — Analyst
Jacob Johnson — Stephens — Analyst
Thomas Flaten — Lake Street — Analyst
Suraj Kalia — Oppenheimer & Co. — Analyst
Presentation:
Operator
Welcome to the BioLife Solutions’ First Quarter 2022 Financial Results Conference Call. [Operator Instructions]
I would now like to turn the conference over to Mr. Troy Wichterman, Chief Financial Officer. Please go ahead, sir.
Troy Wichterman — Chief Financial Officer
Thank you, Rocco. Good afternoon, everyone, and thank you for joining this call. Joining me on today’s call are Mike Rice, Chairman and Chief Executive Officer and Rod de Greef, President and Chief Operating Officer. Earlier today, we issued a press release announcing our financial results and operational highlights for the first quarter of 2022.
As a reminder, during this call, we may make certain projections and other forward-looking statements regarding future events or the future financial performance of the company or its acquisitions. These statements are subject to risks and uncertainties that may cause actual results to differ materially from expectations. For a detailed discussion of the risks and uncertainties that affect the company’s business and that qualify as forward-looking statements, I refer you to our periodic and other public filings filed with the SEC. Company projections are forward-looking statements, are based on factors that are subject to change and therefore these statements speak only as of the date they are given. The company assumes no obligation to update any projections or forward-looking statements, except as required by law.
During this call, we will speak to non-GAAP or adjusted results. Reconciliations of GAAP to non-GAAP or adjusted financial metrics are included in the press release we issued this afternoon. These non-GAAP or adjusted financial metrics should not be viewed as an alternative to GAAP. However, in light of our M&A activity, we believe that the use of non-GAAP or adjusted metrics provides investors with a clear view of our current financial results when compared to prior periods.
Now, I’d like to turn the call over to Mike Rice, Chairman and CEO of BioLife Solutions.
Michael Rice — Chairman & Chief Executive Officer
Thank you, Troy, and good afternoon, everyone. Thank you for joining our call. After my remarks, Tory will present our financials for Q1, then Rod will provide an update on key operational initiatives he is managing targeting gross margin improvements specifically for our Stirling ULT freezer platform. And after that, we’ll be glad to take your questions.
Turning to Q1 revenue and customer highlights. Our team delivered another strong quarterly revenue performance, even more so considering the macro headwinds and specific supplier issues with regard to Stirling that we continue to experience and address. Total revenue was $36.2 million, up 115% from Q1 2021 representing organic growth of 45% and continued strong biopreservation media revenue growth of 53%.
While we had more than a dozen cryogenic freezer orders, totaling over $1 million in revenue, that didn’t ship in Q1 due to a mix of supply constraint issues and customer acceptance timing, these orders have either shipped or are expected to ship in Q2. These delayed orders and overall demand created a significant backlog entering Q2 and we’re aggressively working through the backlog, and at this point are tracking to our internal plan for Q2.
I’d also like to echo the strong growth sentiments in the cell and gene therapy space that other life science tools companies have expressed on their recent earnings calls. From our view, despite the depression of valuations across the sector, CGT is poised for explosive growth over the next few years and the BioLife Solutions portfolio plays a vital role in improving quality and reducing risk. We’re focused on optimizing and scaling our operations to meet anticipated demand for our tools and services.
Our growth catalyst and business fundamentals are strong and we are affirming our full-year 2022 guidance, including unplanned expectations to return to positive adjusted EBITDA by the end of the year, which Troy will cover in a few minutes. Importantly, and turning to operations, I want to express my confidence and appreciation in the strong execution from our operations, quality and engineering teams who leaned in, got a handle on integration demands of the Stirling acquisition and continue a sustained commitment to optimize our production processes, supply chains and QC and QA functions. Critical to continuing to deliver the highest standard of quality and service in our industry and feeding the customer demand we are experiencing, we realized important sequential improvements in gross margin and adjusted EBITDA, and remain confident that we’ll continue to see the sequential improvement throughout the rest of the year.
Turning back to the customer and revenue side of the business in Q1, we gained at least 189 new customers across our 3 product and services platforms, and to remind you now those are. First, cell processing, which includes biopreservation media and Sexton cell processing products. Second, our freezers and Thaw Systems platform comprised of liquid nitrogen freezers and Stirling ULT mechanical freezers and automated thawing devices. And finally, storage and cold chain services, which includes our SciSafe storage services and our evo Cold Chain Management offering.
New Q1 customers by product line included 23 now using biopreservation media, 7 new ThawSTAR users, 7 new evo Cold Chain end users, 25 new cryogenic freezer customers, 98 new Stirling ULT freezer customers, 25 new biostorage customers and 4 new cell processing customers now using Sexton products. As a reminder, for the full year 2021, we gained at least 700 new direct customers and we also benefit from very productive distributors, with our 2 largest having sold and shipped our biopreservation media products to more than 4,200 unique end customers last year.
Now I’ll make some qualitative comments about our 3 revenue platforms, and let Troy speak to revenue for each. For cell processing in Q1, we gained 27 new customers and received confirmation that our cell processing media products will be used in at least 12 additional clinical trials for new cell and gene therapies. We estimate our biopreservation media products have been incorporated in more than 540 customer clinical applications, up from 450 at the end of 2020. For biopreservation media, we also remain confident that each customer clinical application, if approved, could generate annual revenue in a range of $500,000 to $2 million. To-date, our biopreservation media is used in 10 approved therapies and our Sexton cell processing media and vials are used in 3 approved therapies. Our biopreservation media products are also embedded in at least 10 additional CGT applications for which BLA or other regulatory approval filings are expected to be submitted this year and next year.
I’ll conclude by saying that our biopreservation media clinical customer base includes most of the CAR T-Cell developers with our products embedded in a majority of the autologous and allogeneic platforms currently in development. We expect to be able to continue to take share from homebrew preservation cocktails as awareness grows of the critical role our engineered media formulations can play in reducing risk for CGT companies. We also see the recent and pending approvals of CGT products for first and second-line treatments and approvals for new indications as 2 growth catalyst for our biopreservation media and other solutions.
Turning to our freezers and Thaw Systems platform. Again, we gained 130 new customers, including several notable cell and gene therapy and biotech companies. We remain hyper-focused on improving quality and reducing cost of our Stirling ULT freezer products. The residual supplier and quality issues we are addressing are a result of customer demand that saw our ULT team more than double unit production in 2021 compared to 2020. We shipped nearly 8,000 freezers last year and this demand surge strained our supply chain and exposed some latent quality issues of an under scaled Stirling that we inherited. Rod will speak in more detail in our recovery and mitigation activities.
Importantly, demand remained strong and we’re working very hard to to reduce lead times with the goal of 2 to 3 week lead times for new orders by the end of June. As an update to a topic from our last call, we executed a new agreement with our largest ULT freezer distributor to add our CBS liquid nitrogen freezer portfolio to their BioLife offering. We’re excited about the potential of this agreement and related sales and marketing activities to capture growth opportunities for LN2 freezers and we’ll have more to say about this throughout the rest of the year.
In our final 3 revenue platforms, stores and cold chain services, which includes evo Cold Chain rentals and SciSafe storage services, we gained 32 new customers in Q1, that’s 25 for storage services in 7 for evo. Our SciSafe storage services platform is growing rapidly and we remain very optimistic about our ability to profitably scale this platform to meet demand. Our opportunities list of potential new storage services customers is robust and we continue to assess locations for a new U.S. bio repository.
This morning we issued a press release about a new co-marketing agreement and revenue-sharing agreement we executed with Coriell Institute of Medical Research, wherein in both parties will cross-market our respective storage services and bioprocessing and cell analytic services. We believe this combination of complementary services will benefit biotech researchers and companies and we look forward to reporting on this initiative later in the year once the program is in full swing.
With our evo Cold Chain Management platform, cell and gene therapy companies now have full optionality to to access our class defining offering through our expanded specialty carrier partner network. That now includes World Courier, Quick International, Patheon, Marken and Biocair. Q1 evo shipments were up 60% over the same period last year. We have several evaluations and validations underway and expect continued growth in the platform. Evo Shippers are now being used to transport ACS collection, CAR T-Cell therapies, umbilical cord blood and other blood components including plasma and other biologic materials. The list of end users of evo is really a market group of the leading CGT companies. As I mentioned before, we believe most CGT companies will move to validate and approve more than one shipping container and logistics partner over the next few years and that our evo platform will emerge as a leading selection.
Before I turn the call over to Troy to present our financials for Q1. I’d like to provide comments on some other current activities. First, in a couple of weeks we’ll be holding our inaugural Global Innovation Summit, where all of our hardware and software engineering teams and our marketing team will come together to review the CGT manufacturing, storage and distribution workflows and the various innovations our smart folks are working on to better address unmet needs to further reduce risk for our customers. Through our acquisitions, we’ve assembled the world-class team of experts and I fully expect us to identify additional areas where we can further innovate to optimize current practices and add value to our customer operations. This is a mid to long-term strategy session to augment the near-term products we’re developing. We’ll have much more to say on this when appropriate about result in new products and development projects at M&A from the Innovation Summit.
One specific product line I can speak to is our liquid nitrogen high-capacity controlled rate freezer offering. Last week we exhibited and presented at the ISCT Conference in San Francisco and our flagship high capacity rate freezer was the star of the show. We wrote 75 of total leads at the conference and 9 specifically for high capacity rate freezers. We also have 3 additional models of various payload capacities in our new product development plan.
Now, I’ll pass the call over to Troy.
Troy Wichterman — Chief Financial Officer
Thank you, Mike. Revenue for the first quarter totaled $36.2 million, representing a 115% increase over 2021 first quarter revenue. Organic revenue increased 45% in Q1 2022 compared to Q1 2021, driven by biopreservation media revenue of $13.7 million, which was up 53% in Q1 2022 compared to Q1 2021. COVID-19 related revenue accounted for approximately 10% of total revenue in the first quarter.
Cell processing platform revenue was $14.9 million, up 67% over the same period in 2021, organic growth was 53%. Freezers and Thaw System platform revenue was $15.3 million, up 216% over the same period in 2021. COVID-19 related revenue accounted for approximately 4% of the freezer and Thaw Systems platform revenue. Organic revenue was down 3% due to supply chain constraints and COVID related customer acceptance delays in our cryogenic freezer platform. Adjusting for this delayed revenue, which we expect to recognize in Q2, organic revenue for this platform would have been up 23% compared to the same period in 2021. Storage and storage services platform revenue was $6 million, up 95% over the same period in 2021. COVID-19 related revenue accounted for approximately 52% of the storage and storage services platform revenue. Organic growth was 95%.
Adjusted gross margin for the first quarter of 2022 was 33% compared with 55% for the first quarter of ’21 and 18% for the fourth quarter of 2021. The positive impact sequentially was largely due to lower warranty expense at our ULT platform as well as favorable product mix. And we expect to see a positive impact on margin throughout 2022 due to leveraged operational overhead and the benefits of our supply chain efforts which Stirling did not have in place previously.
Adjusted operating expenses for Q1 2022, totaled $19.8 million compared with $8.8 million in Q1 2021. The increase in operating expenses was primarily driven by the absorption of operating costs related to our Stirling and Sexton acquisitions. In addition, operating expenses increased due to increased accounting costs associated with large accelerated filer status as well as increased head count and stock-based compensation expense necessary to support our overall growth objectives. Our adjusted operating loss for the first quarter of 2022 was $8 million compared with adjusted operating income of $494,000 in Q1 2021.
Adjusted EBITDA for the first quarter of 2022 was negative $814,000 compared with positive $2.8 million for the first quarter of 2021, and negative $5.5 million for the fourth quarter of 2021. We expect this number to steadily improve throughout the year resulting in a full year 2022 positive adjusted EBITDA.
Our cash balance at March 31, 2022 was $59.5 compared to $69.9 million at December 31, 2021. Taking into consideration our adjusted EBITDA of negative $800,000, cash used in Q1 2022 was related to unfavorable working capital adjustments of $7.3 million which was primarily due to timing and capital expenditures of $2.3 million including build-outs of our bio repository facilities.
Turning to 2020 revenue guidance. Management affirms full-year guidance to be in the range of $159.5 million to $171 million reflecting year-over-year growth of 34% to 44% and organic growth of 28% to 39%. COVID-19 related revenue is expected to account for approximately 8% to 9% of total revenue.
Total revenue expectations for 2022 include the following platform contributions. Cell processing platform is expected to be between $64 million to $67.5 million, an increase of 42% to 50% over 2021 and organic growth of 30% to 35%. Freezers and Thaw Systems platform is expected to be between $74 million to $77.5 million, an increase of 31% to 37% over 2021, and organic growth of 28% to 39%. COVID-19 related revenue is estimated to account for less than 5% of the freezer and Thaw Systems platform revenue.
Storage and storage services platform total and organic revenue is expected to be between $21.5 million to $26 million, an increase of 22% to 48% over 2021. COVID-19 related revenue is expected to account for an estimated 40% to 50% of the storage and storage services platform revenue. The COVID-19 related revenue is based on contracts, and therefore we do not expect to see variability on this number through the balance of the year.
Finally, in terms of our new share count, as of today, we have 42.4 million shares issued and outstanding and 44.4 million shares on a fully diluted basis.
Now, I’ll turn the call to Rod.
Rod de Greef — Chief Operating Officer
Thanks, Troy. As we discussed in our last earnings call, my main focus in stepping back from the CFO role and turning the reins over to Troy, who by the way is doing an excellent job, has been addressing and correcting the near-term supplier quality and production issues at the Stirling facility in Athens, Ohio.
What we inherited in the transaction and recognized quickly once inside was that Stirling had experienced tremendous growth, which as a reminder, was a 100% increase in unit production between 2020 and 2021, and they had not scaled to accommodate that growth on multiple levels. with the commitment and effort of a lot of people at that facility as well as the experience the BioLife team brings to bear, we’ve made good progress on all fronts, which has resulted in a modest, but positive like-for-like sequential increase in gross margin for that product line.
While we still have a lot of work to do, we’re on the right track and regular and consistent progress is being made, which I believe will have a further positive gross margin impact as we move throughout the year. Acquisitions and integrations present new and different issues, and I’m confident that we have our arms around this and are on the right path going forward.
Over the last several weeks, I have been able to shift some of my focus to spend some time at our 3 manufacturing sites as well as our newly opened biostorage facility in Amsterdam. While there are always opportunities for operational improvement, in general, these operations are running smoothly with no material issues outside of a number of external supply chain constraints similar to what many companies in our industry and others are facing.
A prime example of this kind of situation is the key vendor for our LN2 freezer line who had both labor and supplier issues during this quarter, which negatively impacted their ability to deliver a key component to us in the quantities we have had on order since last year. This in turn impacted freezer production and revenue by approximately $650,000 in the quarter. Several months ago, we entered into a supply agreement with a secondary vendor, but based on the lead times for this unique custom item, we don’t expect product from them to flow until late this quarter or early Q3. But we have now secured dual source supply of this critical component, which would mitigate any supply chain risk in this area going forward.
A top priority for our VP of Supply Chain Management is to implement dual sourcing on as many components and raw materials as possible across our product platforms and we are well into that initiative. This is always a smart move, but in these unprecedented times it’s becoming even more critical. Fortunately, alternatives exist for most things, and we plan to have maximum redundancy in place by the end of the year.
We’ve also discussed another key objective on previous calls of establishing a revenue-generating service offering and that we have a pilot program up and running, although minimally staffed at this point. In Q1, this program generated approximately $79,000 in revenue with one dedicated FTE, and we’re confident that there is a strong high margin revenue opportunity as we finalize the offering initially for the freezer line and build-out our field service organization throughout this year and into next.
Finally, I’ll take a moment to address the near-term delay experienced with our ERP implementation, which resulted from our delayed 10-K filing. While frustrating for sure, we’re now at a point where the accounting side of NetSuite is expected to go live for a number of our subsidiaries later this week, post our 10-Q filing. The balance of the implementation plan is coming together and we continue to expect to have the full accounting and manufacturing applications up and been running by the end of the year, and Middleware connectivity to numerous other applications entity-wide by Q1 of next year.
In closing, I’d like to reiterate that we’ve made good progress on working through the Stirling issues and with the other opportunities for improvement we have in front of us, I expect to be able to report continued progress on a quarterly basis.
Now I’ll turn the call back over to Mike.
Michael Rice — Chairman & Chief Executive Officer
Thanks, Rod. So the key takeaways I’d like to leave you with are. Number one, demand for our portfolio of class defining bio production tools and services remain strong and we fully expect to meet or beat our full year revenue guidance. Number two, we expect to demonstrate continued sequential improvements with the operations and margins in our ULT freezer platform and to realize positive adjusted EBITDA for the entire business by the end of the year. And number 3, we’re focused on innovative new product launches for this year and next, and are seeing tangible and real signals of lift off in the cell and gene therapy.
The last comment I want to make before taking questions is that we believe in the growth ahead for the business. The value of BioLife and our alignment with you, our shareholders. With that, several members of our leadership team including myself, have agreed to accept BioLife stock in lieu of part of our salaries. Our Board members have also agreed to accept BioLife shares in lieu of their cash board fees. We’re all fully confident we will continue to grow the business in this environment where our catalyst and business fundamentals are strong and intact, and we look forward to being rewarded in line and accordingly.
Related to this, apart from some occasional sell to cover stock sales transactions to cover taxes for upcoming vesting events, my longstanding portfolio diversification plan sales are now complete. This is a great moment for BioLife and the cell and gene industry in a difficult macro and public market environment. But I’m pleased to say that overall product demand so far in Q2 is strong and we’re looking forward to sharing our results on our Q2 earnings call.
Now I’ll turn the call back over to the operator to take your questions. Rocco?
Questions and Answers:
Operator
Thank you. [Operator Instructions] Today’s first question comes from Max Masucci with Cowen and Company. Please go ahead.
Max Masucci — Cowen — Analyst
Hi, thanks for taking the questions. Mike, first one, you called out the dislocation between the high growth that we continue to see and the cell and gene therapy end markets, the weakness we’ve seen in the public arena, say if we take a step back here, you look at the company’s revenue growth trajectory here in 2022, the gross margin recovery that’s underway. What gave you the confidence to swap stock for cash compensation? And we’ll be curious to hear if there is any limit to the percentage of stock that you’re leadership team could swap?
Michael Rice — Chairman & Chief Executive Officer
Yeah. Thanks, Max, and a really good question. I’m glad to offer some other color comments. I fully believe in the business, the team here, our ability to execute and at these silly depressed share prices, I’m looking to accumulate as many shares of BioLife stock as I can. And you know it’s going to range by individual, Max, from 50% to 100% will come in the form of stock as opposed to cash.
Max Masucci — Cowen — Analyst
Got it. Moving to the co-promote. Is there any detail you can provide around the makeup and the profile of Coriell, your partners customer base, whether the co-promote gives you increased exposure to any specific customer types or geographic regions where you were previously under-exposed? And then any detail around the structure of the agreement and the split of revenue sharing will be great.
Michael Rice — Chairman & Chief Executive Officer
Sure, I’ll start with the last one. It goes like this, whoever originates, obviously gets a little finders fee, and if that originator does the work, meaning the service they can provide they get, again, most of it. But if not, it’s sub single or mild single digits for the referral fee and all the rest goes to the other party, depending on who does the work. Max, with respect to Coriell’s customer base and highly aligned with some of the broader biopharma companies we’d like to crack into, I can say candidly, there have been some storage opportunities over the last few years with SciSafe that we’ve bid on, but didn’t win, because we couldn’t offer comprehensive cell analytic services, and now we can through a world-class partner. So that’s going to be great, I don’t see us no bidding on any opportunities now, now that we’ve got this agreement in place. So really excited about it, but it’s going to be focused on customers who need storage and they need some tumor analysis, DNA extraction and other analysis on the cell types, whether it’s to characterize master cell banks, working cells or things like that.
Max Masucci — Cowen — Analyst
Okay. Final one here for Troy and Rod, and nice to see the gross margin recovery. As we just fine tune the gross margin expectations in our models, is there any additional detail you can give us in terms of the pacing we should expect on the gross margin front in the coming, call it, three quarters? And whether there are any other gross margin swing factors that we should be taking into consideration?
Troy Wichterman — Chief Financial Officer
Thanks for the question, Max. Yeah, so as I addressed in my commentary, we do expect sequential modest improvement in gross margin. And to address your question on the margin swings, we do not anticipate any big swings one way or the other on the gross margin side at this point in time.
Max Masucci — Cowen — Analyst
Got it. Thanks for taking the questions.
Michael Rice — Chairman & Chief Executive Officer
Thanks Max.
Operator
Ladies and gentlemen, our next question today comes from Jacob Johnson at Stephens, Inc. Please go ahead.
Jacob Johnson — Stephens — Analyst
Hey, good afternoon everybody.
Michael Rice — Chairman & Chief Executive Officer
Hey, Jacob.
Jacob Johnson — Stephens — Analyst
Hey Mike. Maybe starting on Stirling, it seems like the business development trends are really strong there. Can you talk about any impact from these operational issues on kind of selling these Stirling freezers, it doesn’t sound like you’ve seen any? And then your ability to deliver on that, the demand you’re seeing there?
Michael Rice — Chairman & Chief Executive Officer
Yeah. Sure, Jacob. I will say that while we’re in this relative precarious position, where I would say appropriately nervous about every order, but we’re confident that we’ll be able to retain nearly all the orders. Some customers just as in Q4 and in some cases in Q1, some customers couldn’t wait, so they had to buy something from somebody else, but we have not seen, we have not seen any massive erosion or order cancellations. To the contrary, I think the efforts of our sales team and just the incredible degree of integrity that they have being transparent with our customers about what’s wrong and what we’re doing to fix it, they are preserving a backlog and they are continuing to generate new orders. So, so far so good. We just can’t get through it fast enough, let me just say it at that way.
Jacob Johnson — Stephens — Analyst
Got it. Understood. And then evo 60% growth in shipments year-over-year. So it seems like you and your courier partners are seeing traction there. I’m just curious as we think about the volumes there, how much of that is kind of you’re getting into early stage clinical trials, how much of it is kind of second sourcing wins of commercial therapies. Maybe just kind of talk about where you’re seeing traction with new customers on the evo side?
Michael Rice — Chairman & Chief Executive Officer
Yeah, Jacob, super-insightful question. Most of the evo shipments are transporting and approved CAR T-Cell therapy or the Zolgensma approved gene therapy, and then the bulk of the rest are all early stage, early clinical trial phase customers. And that list of the number of customers and the names of those customers is long and very well known. So I think it’s all going the right way here. The other evo validation underway by a company with two approved CAR Ts continues to rock and we look forward to reporting on that hopefully later in the year.
Jacob Johnson — Stephens — Analyst
You answered my next question, so I’ll leave there. Thanks, Mike.
Michael Rice — Chairman & Chief Executive Officer
Sure.
Operator
Ladies and gentlemen, our next question today comes from Thomas Flaten with Lake Street Capital Markets. Please go ahead.
Thomas Flaten — Lake Street — Analyst
Great. Thanks for taking the questions. Hi, guys.
Michael Rice — Chairman & Chief Executive Officer
Hi, Thomas.
Thomas Flaten — Lake Street — Analyst
Two quick questions. Mike, in your prepared comments you mentioned, I don’t want to paraphrase, taking share from the homebrew market with media. Do you have a sense of the growth that you’re seeing, how much is just the tide lifting all boats versus you’re taking share, do you have any, I mean, I don’t know if you can quantify, but any qualitative comments you have around that?
Michael Rice — Chairman & Chief Executive Officer
Sure. I think Thomas that we are taking share. I think that we are seeding the use of CryoStor or HypoThermosol in the research-use only market, some of which will translate into clinical, also the pure clinical markets and then the later stage clinical trial phase projects, which hopefully will get over the goal line here in the next couple of years or so. I think we’re definitely seeing more uptick, more attraction and I think that as new groups get formed or spun-out of academic centers or clinical centers that they are defaulting to using CryoStor versus defaulting to use a homebrew.
Now I can’t quantify that with any sort of precision, but that’s just my sense when I connect with Aby Mathew, our CSO and EVP, and I think back to just an hour or so ago when he came in and gave me an update on the ISCT Conference, and all the people that lined up to talk to him and the other parts of our team, I mean, just tremendous amount of exposure and awareness of what we’ve got here, and frankly, because a lot of people haven’t traveled for the last couple of years, much more awareness into discovering that BioLife is a much different company with a much broader portfolio.
So I think the way we run the playbook to get media adopted in CGT is clearly going to pay off. And again, the thesis of our acquisition strategy to leverage those sticky media customers, to sell them more things in the portfolio, I fully expect us to realize that and execute on that as well throughout the year. So good to be back, good to be out in front of people and feeling really good about what’s going on across the platforms.
Thomas Flaten — Lake Street — Analyst
Great. And then one related to the new facilities that you open, have opened Amsterdam, Massachusetts and New Jersey, any sense of what the or I’m sure you know that the customers, new customers, old customers relocating. Just trying to get a sense of how those new facilities are being utilized by your customer base.
Michael Rice — Chairman & Chief Executive Officer
Sure. It’s a mix. Thomas, it’s a mix of existing customers that are giving us much more business and many more projects to store, whether they are existing or brand new or whatever, but just getting much deeper for sure. And then obviously, new customers, de novo, who are coming to us for the first time, who’ve made that decision to outsource storage versus trying to take it out and how and it’s everything that goes along with that.
Thomas Flaten — Lake Street — Analyst
Excellent. Appreciate the questions. Thanks.
Michael Rice — Chairman & Chief Executive Officer
You’re welcome.
Operator
[Operator Instructions] Our next question comes from Suraj Kalia with Oppenheimer. Please go ahead. Suraj, your line is open.
Suraj Kalia — Oppenheimer & Co. — Analyst
Mike, Rod, can you hear me alright?
Michael Rice — Chairman & Chief Executive Officer
Hi, Suraj. Yes we can.
Rod de Greef — Chief Operating Officer
Hi.
Suraj Kalia — Oppenheimer & Co. — Analyst
Sorry, apologies, I’m having some phone issues.
Michael Rice — Chairman & Chief Executive Officer
No problem.
Suraj Kalia — Oppenheimer & Co. — Analyst
Hey Mike, just hopping in between calls, I believe I heard you say 75 or so leads for high-capacity freezers that you all have picked up, did I get that right?
Michael Rice — Chairman & Chief Executive Officer
Somewhat. I said 75 total leads at ISCT last week in San Fran, and 8 or 9 for high-capacity freezers.
Suraj Kalia — Oppenheimer & Co. — Analyst
Mike, how much of your guidance is predicated on meeting any or some off these leads?
Michael Rice — Chairman & Chief Executive Officer
Thanks for asking. Zero, it’s all upside, Suraj.
Suraj Kalia — Oppenheimer & Co. — Analyst
So this would be all upside. Fair enough.
Michael Rice — Chairman & Chief Executive Officer
Yeah.
Suraj Kalia — Oppenheimer & Co. — Analyst
Mike, one of the things that has been lost in the discussion about freezers and ULTs is the Thaw Astero Bio, the Thaw System, how is the performance of the Thaw System been? And also specifically on the freezers, can you give us a relative framework on year-over-year unit growth, customer growth, I’m more interested in the unit growth on the freezer side, specifically?
Michael Rice — Chairman & Chief Executive Officer
Sure. Let’s start with that. You may have heard Rod’s comments from a few minutes ago, I’m not sure, but Suraj, in 2021 versus 2020 we doubled ULT freezer production. So we shipped about 3,500 or so in 2020 and nearly 8,000 in 2021, a fair amount of that was COVID lift transporting vaccines and that, but nevertheless, just phenomenal freezer unit capacity and production there. On the CBS side, the LN2 side, not nearly to that scale, but nice decent growth for sure.
Suraj Kalia — Oppenheimer & Co. — Analyst
Got it. And Mike, in terms of the management and Board comp till August in terms of stock, it’s an interesting move, and I’d love to get your perspective, what was the primary driver, was it some inbound concern, obviously, you all are telegraphing confidence based on the guidance, and I’m curious, when you layer on this comp, or the stock comp, just kind of give us some perspective on the shift, because I haven’t heard anyone else go down this route? Gentlemen, thank you for taking my questions.
Michael Rice — Chairman & Chief Executive Officer
Yeah. Thanks, Suraj, and a good question. Typically, as you know, when we see this, it’s because companies are distressed, or they’re going to run out of money or something, that’s not the case at all here. To the contrary, our business fundamentals are intact and at these, I use the word silly, I’ll just call it stupid at these stupid prices for BioLife, we want to do everything we can to convey confidence and our ability to execute and to be rewarded commensurately with all shareholders if we do execute. So the prospect of taking shares at $10 or $11 or $12 or $13 is really meaningful, I’m glad to do that for at least 3 months and we’ve got a number of senior leaders here who are signing up for the program in addition to all the Board members. So it’s nothing more than that, it’s about sending a signal that we are fully, fully confident in our ability to grow the business to meet or beat this year’s guidance and to turn BioLife into something that is much more value than what it is today. We can’t fix everything, the macro trends are so strong, but all we can do is win or lose in our own lane and this is one way that we intend to do that.
Suraj Kalia — Oppenheimer & Co. — Analyst
Great. Thank you.
Operator
And ladies and gentlemen, this concludes the question-and-answer session. I’d like to turn the conference back over to Mike Rice, Chairman and CEO for closing remarks.
Michael Rice — Chairman & Chief Executive Officer
Thank you, Rocco, and thanks again everyone for your interest in BioLife. We remain confident in meeting or exceeding our 2022 revenue guidance and in reaching our stated mid-term financial goals. Thank you for your support of BioLife. Good evening, everyone.
Operator
[Operator Closing Remarks]