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Precision BioSciences (DTIL) Swings to $1.05 EPS in Q4, Reversing $2.22 Year-Ago Loss

Precision BioSciences swings to $1.05 EPS profit in Q4 2025, reversing year-ago $2.14 loss, as revenue holds flat at $34.2M.

March 12, 2026 2 min read
Tencent

Precision BioSciences swings to $1.05 EPS profit in Q4 2025, reversing year-ago $2.14 loss, as revenue holds flat at $34.2M.

Earnings Per Share (GAAP)
$1.05
Revenue
$34.2M

Precision swings to profit. Precision BioSciences reported GAAP diluted EPS of $1.05 for Q4 2025, a dramatic reversal from the year-ago loss of $2.22 per share. The biotech posted net income of $20.1 million, compared to a loss last year. The swing from loss to profitability represents a fundamental shift in the company’s financial trajectory.

Revenue holds flat sequentially. The company generated $34.2 million in revenue. For a biotechnology company, the path to sustained profitability typically requires either expanding partnership revenue or advancing clinical programs toward commercialization. The stock traded at $5.35 with volume of 236,044 shares, showing muted reaction to the results.

Historical context matters. The Q4 profit stands in sharp contrast to Precision’s recent history: the company posted losses in the three prior quarters. Investors will need to determine whether this marks a sustainable inflection point or a temporary boost from non-recurring items.

What to Watch: The earnings call and press release details will reveal whether management expects to sustain positive earnings in 2026.

This article was generated using AlphaStreet’s proprietary financial analysis technology and reviewed by our editorial team.

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