— General and administrative expenses were $4.1 million during the year ended December 31, 2019, up 21% from last year, primarily due to increased legal fees and salaries and benefits expense.
— The company is in the process of initiating a phase 1 study of second pipeline candidates in the first half of this year to evaluate the ability of BP1002 to treat refractory/relapsed lymphoma and chronic lymphocytic leukemia patients.
— The company is nearing completion of an investigational new drug (IND)-enabling studies of BP1003 for the treatment of solid tumors, including pancreatic cancer, and expects to file an IND application for phase 1 study in 2020.
— Following the successful completion of the safety testing in Stage 2 of phase 2 clinical trial of prexigebersen in acute myeloid leukemia (AML), the company now plans to advance this program to its next stage in the first half of 2020.
— The company filed an IND application for prexigebersen in the treatment of solid tumors including ovarian and endometrial cancer and expects to start that study later this year.